Biospecimen Procurement and Translational Pathology Shared Resource Facility (BPTP SRF)
Director: Therese Bocklage, MD
Scientific Associate Director: Derek Allison, MD
The Markey BPTP SRF collects, processes, annotates, stores and distributes biospecimens to support translational research in cancer and other diseases. Markey BPTP SRF support includes assistance in obtaining IRB certification, specimen queries, as well as the acquisition, processing, and send-out of targeted biospecimens in accordance with specific research protocols. We also maintain a full-service histology and IHC laboratory dedicated to research, which includes tissue microarray services and access to UK surgical archive materials, as well as molecular assays (in situ, TUNEL), Nanostring GeoMx Digital Spatial Analysis, and Halo/Halo AI image analysis. Our services are available to University of Kentucky (UK) faculty and other qualified investigators in partnership with UK faculty.
Prioritization of Services
The prioritization of services is based on the following criteria:
- MCC members with cancer-related, peer reviewed studies.
- MCC investigators preparing cancer-related, peer reviewed grant applications.
- MCC pilot/feasibility projects.
- MCC investigators not currently funded by peer reviewed grants.
- Non-cancer-related studies.
Request BPTP SRF Services
The BPTP SRF now uses the online program iLab to manage all service requests and billing, including:
- Prospective Specimen Collections
- Frozen or fixed specimen requests
- Tissue Microarray requests
- Histology and IHC
- Self-serve Histology Equipment Reservations (microtome and cryostat)
- Halo Workstation Reservation
- Nanostring GeoMx Digital Spatial Analysis (Consult required)
- Specimen queries, feasibility queries, letters of support, budgets
To request any BPTP SRF services, visit the iLab landing page with more detailed instructions, including a one-time account setup.
For questions or help in setting up your iLab account, or to schedule a consultation, please contact BPTP by email.
Investigators are required to acknowledge the Markey Cancer Center Biospecimen Procurement and Translational Pathology Shared Resource Facility (BPTP SRF) in any publications that result from the use of biospecimens or information received through the MCC BPTP SRF. For your convenience, you are welcome to use the following statement:
“This research was supported by the Biospecimen Procurement and Translational Pathology Shared Resource Facility of the University of Kentucky Markey Cancer Center (P30CA177558).”
Frequently Asked Questions
What information comes with the specimens?
The type of information depends on what is requested by the investigator. In collaboration with Markey Cancer Research Informatics SRF, the Biospecimen Procurement and Translational Pathology Shared Resource Facility (BPTP SRF) can provide disease type (or control), age, gender, staging, histological diagnosis, smoking history, region, etc., with most specimens. Personal identifying information is not available to investigators
Is clinical history or follow-up information available?
Clinical history and follow-up data for cancer patients is generally available, with IRB approval, through a partnership with Markey Cancer Research Informatics and the Kentucky Cancer Registry/SEER database. Please contact the BPTP for more information.
How do I get IRB approval?
What is ORIEN Avatar and how can I access data?
BPTP, in collaboration with Markey’s Precision Medicine Group, submits tumor and germline sequencing from eligible patients consented to the Markey Total Cancer Care Protocol for research grade whole exome sequencing and RNASeq. Learn more about the ORIEN protocol or submit a data request.
Contact BPTP SRF Staff
Personnel and Contact Information
Derek Allison, MD
BPTP SRF Scientific Associate Director
William R. Willard Medical Education Building
Lexington KY 40536-0093
BPTP Program Administrator
Combs Research Building, 108B
Lexington, KY 40536-0093
Additional information about the Markey SRFs can be found at the links below. SRF service information can be found by logging into iLab.