Chronic Lymphocytic Leukemia (CLL) targeted therapy

Targeted drugs, often paired with chemotherapy, are designed to take advantage of the specific vulnerabilities of your cancer cells. Your cancer cells are tested to determine which targeted drugs may be helpful.

The most common targeted therapy drugs used are:

  • Rituximab (Rituxan)®
  • Alemtuzumab (Campath)®
  • Ofatumumab (Arzerra)®
  • Obinutuzumab (Gazyva)®
  • Ibrutinib (Imbruvica)®
  • Idelalisib (Zydelig)®
  • Venetoclax (Venclexta)®

Rituximab, ofatumumab and obinutuzumab are given intravenously. Alemtuzumab is given either intravenously or by an injection just under the skin. Ibrutinib is given as a capsule by mouth. Idelalisib and venetoclax are given as a tablet by mouth.

Learn more

For more information on diagnosis, treatment and more of chronic lymphocytic leukemia, visit our CLL information pages below.

Markey Cancer Center is NCI-designated

The UK Markey Cancer Center was first designated by the National Cancer Institute in 2013 – a distinction that recognizes our extraordinary ability to provide world-class care for our patients. We are the only NCI-designated cancer center in Kentucky and one of only 71 in the nation.

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