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Faculty Name
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Project Name
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Web
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Adams, Val
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EGFR Targeted Nanoparticles to Overcome Paclitaxel-Resistant Breast Cancer
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profile
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Ain, Kenneth
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Novel Chemotherapy of Radioiodine-Unresponsive Thyroid Carcinomas; Sodium-Iodine Symporter Transcriptional Repression
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profile
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Alexander, Linda
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Organizational, Cultural and Individual Barriers Associated with Utilization of a Worksite Tobacco Cessation Program
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profile
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Anderson, Bradley
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Anti-topoisomerase aerosols for lung cancer therapy; combinatorial development of blood-stable Camptothecins
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profile
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Andrykowski, Michael
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Psychological and Behavioral Impact of Cancer Screening and Cancer-Related Fatigue
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profile
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Anthony, Lowell
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Neuroendocrine Oncology
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profile
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Armstrong, Debra
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Breast and Cervical Cancer Coalitions
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profile
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Arnold, Susanne
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ChemoRx & Low Dose Radiation for SCLC, NSCLC, Head & Neck Cancer, Metastatic Disease; 5th District Lung Cancer Program
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profile
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Bae, Younsoo
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Multifunctional Nanoassemblies for Cancer Targeted Combination Drug Delivery
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profile
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Bayliff, Sherry
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Management of Children with Attention Impairment following Cancer Treatment
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profile
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Beck, Sandra
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Colorectal Surgery
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profile
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Bensadoun, Eric
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Evaluation of solitary pulmonary nodules for malignancy potential
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profile
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Black, Esther
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Genomic DNA Array analysis of oncogenic signaling pathways; MicroRNA expression and responses to chemotherapy
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profile
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Bondada, Subbarao
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Growth & differentiation of B-Lymphocytes; BCR & Co-Receptor signaling & polymorphisms; leukemias & lymphomas
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profile
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Brown, Stephen
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Radioprotective Agents in NSCLC Therapy
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profile
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Bryson, J. Scott
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Growth Reg. and Rx of Leukemias & Lymphomas: Graft-versus-tumor (GVT) and (GVHD); BMT Toxicities in Aging; Allogeneic Rx in Lung Cancer
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profile
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Bummer, Paul
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Development of Dosage Forms and Delivery Systems for Anti Tumor Agents
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profile
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Butterfield, Allan
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Oxidative stress, protein oxidation, lipid peroxidation, reactive oxygen species (ROS) production, mitochondrial dysfunction
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profile
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Chen, Gang
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Heavy metal-induced tumorigenesis
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profile
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Chen, Li
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Cancer biostatistics with an emphasis on medical and epidemiological studies
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profile
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Chen, Min
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Integrin, cell motility and invasion in breast carcinoma
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profile
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Cibull, Michael
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Ovarian Tissue Bank/GOG
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profile
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Clayton, Richard
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Tobacco etiology research network analysis; Tobacco-related health disparities research network (TReND)
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profile
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Cohen, Donald
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Modulation of Anti-Tumor Immunity via IL-10 Production by Non-Small Cell Lung Carcinomas
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profile
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Cohen, Elisia
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Communication-Based Strategies to Eliminate Cancer Disparities
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profile
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Coker, Ann
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Violence against women; HPV vaccine acceptance; cervix cancer in victims of violence
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profile
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Craven, Rolf
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Pgrmc1/Hpr6 Expression and MDR in Breast Cancer; EGFR Targeting in Lung Cancer
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profile
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Crispen, Paul
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Urologic Oncology
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profile
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Crosby, Richard
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STDs (HPV) and tobacco synergwww.mc.uky.edu/obg/FacultyInfo/reproendo/tomcurry.aspy in cervix cancer incidence
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profile
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Curry, Thomas
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Ovarian metalloproetinases and reproductive aging
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profile
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Desimone, Philip
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GI Cancer Clinical Trials
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profile
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Dignan, Mark
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Native Network Cancer Resources Center; ACCN; Go Sun Smart; Nutrition & Physical Activity; KYPRC; Rural Screening
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profile
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D'Orazio, John
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Defining the role of MC1R in UV-induced oxidative damage and DNA repair
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profile
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Durbin, Eric
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KCR Data Matching Project
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profile
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Dwoskin, Linda
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Nicotinic Receptor Antagonists: Development of novel treatments for nicotine addiction
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profile
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Dziubla, Thomas
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Targeted polymer antioxidant nanocarriers for Doxorubicin chemoprotectant
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profile
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Elliott, Gregory
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Development and evaluation of Purine-Based AdSS Inhibitors
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profile
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Eum, Sung Yong
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PCB-Induced Endothelial Dysfunction and Cancer Metastasis
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profile
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Evers, B. Mark
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Molecular mechanisms of gastrointestinal development, growth and malignancy; Functional gene expression & signaling pathways
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profile
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Fannon, Michael
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Computer Modeling of Perlecan as a Vascular Regulator
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profile
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Ferraris, Victor
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Adjuvant Interventions Improving Outcomes for Surgery for Lung or Esophagus Cancer
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profile
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Fleischman, Roger
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Cytokine, Immunotherapy and Chemotherapy for Lymphoma
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profile
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Fleming, Steven
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Breast and Prostate Cancer Patterns of Care Study
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profile
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Fondufe-Mittendorf, Yvonne
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Molecular mechanism of transcription regulation through studies on chromatin structure
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profile
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Fried, Michael
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Cooperative interactions and interchromosomal gene regulation in DNA repair
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profile
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Gairola, Chandrachuranan
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Genetic Polymorphism and Lung Cancer: Animal Models of Tobacco Carcinogenesis
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profile
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Galperin, Emilia
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Functional cross-talk between endocytic and signaling cellular machineries and how this applies to cancer development
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profile
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Gao, Tianyan
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Regulation of PHLPP and its role in tumorigenesis
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profile
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Glauert, Howard
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Antioxidants, Cigarette Smoke, Semi-Volatile PCBs, Hepatic Toxicity/Tumorigenesis, NF-kB, Apoptosis; Nutrition & Prevention of Cancer
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profile
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Greenwood, Martha
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Children's Oncology Group
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profile
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Gu, Liya
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DNA Mismatch Repair Deficiency and Leukemia Relapse
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profile
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Gu, Qihai
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Pulmonary stresses in small cell lung cancer: Neurogenic mechanisms
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profile
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Gul, Zartash
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Hematology and Blood and Marrow Transplant
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profile
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Guo, Peixuan
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Nanobiotechnology and its applications in the therapy of cancer
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profile
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Hahn, Ellen
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Tobacco Policy Research Program and Clean Indoor Air Partnership
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profile
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Hartsfield, James
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Genetic factors associated with ovarian and head & neck cancers
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profile
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Hatcher-Keller, Jennifer
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Promoting Mammography in African American Women Visiting the Emergency Department
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profile
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Hayslip, John
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Phase II - III studies of Chronic Lymphocytic Lymphoma, Non-Hodgkins Lymphoma,
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profile
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Hennig, Bernhard
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Superfund NIEHS: Dietary protection vs oxidative damage from PCBs contributing to chronic disease
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profile
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Hilt, James
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NIRT: Novel Magnetically and Thermally Responsive Nanoparticles for Cancer Treatment
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profile
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Hirschowitz, Edward
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Autologous Dendritic Cell Vaccines in NSCLC; autoantibody markers of NSCLC; novel lung tumor antigens
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profile
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Hopenhayn, Claudia
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Monitoring the Impact of a Prophylactic HPV Vaccine on HPV types in Cervical Cancer using Tissues for Validation
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profile
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Horbinski, Craig
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Mutant Isocitrate Dehydrogenase in Gliomagenesis
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profile
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Hourigan, Jon
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Surgical interventions and adjuvant therapy for colorectal cancer
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profile
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Howard, Dianna
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Targeted ablation of stem cells in leukemias/lymphomas; in vivo model of leukemia stem cells
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profile
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Huang, Bin
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Cancer Incidence Disparities in Appalachia and within Appalachian Sub-regions
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profile
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Huang, Cai
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Cell adhesion, motility, metastasis
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profile
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|
Izumi, Tadahide
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DNA damage, mutagenesis and repair specifically as the result of reactive oxygen species (ROS)
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profile
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|
Jennings, Chester
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Leukemias and Lymphomas: Histopathology of B-cell lymphoma impacted by signal transduction regulation
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profile
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Jia, Jianhang
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Hedgehog signaling; dMST as a tumor suppressor
|
profile
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Jones, Dennie
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Gastrointestinal cancer, lung cancer and neuro-oncology
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profile
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|
Jones, Jeffrey
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Coordinated school health youth risk behavior survey project
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profile
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Kaetzel, Charlotte
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Polymeric Immunoglobulin Receptor Dysregulation in Colon & Lung Cancer; Bacterial-Epithelial Interactions in Colon Inflammation
|
profile
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|
Kaetzel, David
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NM23-H1 Isoform Endonuclease, DNA Repair, Suppression of Mutator Phenotype and Metastasis; PDGF-A gene enhanceosome
|
profile
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Kaplan, Alan
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Hypoxia-driven macrophage-mediated immunotherapy of lung cancer; T-cell regulation; modulation of GVHD and GVL in BMT
|
profile
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Kenady, Daniel
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TNFerade Biologic with-5-FU and Radiation Therapy for Advanced Pancreatic Cancer; IRX-2 in SCC of the Head & Neck
|
profile
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Kilgore, Michael
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Transcriptional Control of Differentiation, Proliferation & Apoptosis Through PPAR-gamma: Breast Cancer
|
profile
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|
Kim, Kyung-Bo
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Identify/Develop and Validate Novel Drug Targets (AHR, Proteasomes, Angiogenesis) and Targeting Agents
|
profile
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|
Knudsen, Hannah
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Smoking Cessation Practices in Community Tx Programs
|
profile
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|
Kohler, Heinz
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Development of 2nd/3rd Generation Antibodies Against HER-2/neu Receptor in Lung Cancer
|
profile
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|
Kudrimoti, Mahesh
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Risk and Outcomes of Mucositis in Subjects Being Treated for Breast, Colorectal, Head and Neck, Non-small Cell Lung or Ovarian Cancers
|
profile
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|
Kyprianou, Natasha
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Targeted Modulation of Signaling Pathways in Prostate Cancer, BPH, Anoikis and Apoptosis; TGF-B, Quinazolines
|
profile
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|
Lee, Cortney
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Endocrine Surgery with an emphasis on thyroid cancer and disorders
|
profile
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|
Lee, Wooin
|
Functional and Molecular Studies of OATP1B3 in Colon Cancer
|
profile
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|
Leggas, Marcos
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Clinical Development of Anti-Cancer Agents; Pharmacokinetics, Nanoparticles, ABC Transporter, DB-67
|
profile
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|
Li, Guo-Min
|
DNA Mismatch Damage Response Elements in Cancer Prevention/Progression
|
profile
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|
Li, Tonglei
|
Development of Novel Ligand-Drug Hybrid Nanocrystals to Target Breast Cancer
|
profile
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|
Li, Jing
|
PKC, PKD, neurotensin, Rap 1, EPAC, Ox Stress, Rho/ROK/PKC-delta and hedgehog regulation in intestinal cell survival & proliferation
|
profile
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Li, Xiang-An
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The role of scavenger receptor BI in apoptosis
|
profile
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Liang, Ying
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Identifying molecular mechanisms that regulate self-renewal and differentiation of hematopoietic stem cells in normal, aging and cancerous conditions
|
profile
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|
Liu, Chunming
|
B-Catenin, APC, Wnt signaling and colon tumorigenesis
|
profile
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Luo, Guangxiang
|
Mechanism of Hepatitis C Virus Infection and Replication
|
profile
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Luo, Jia
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Alcohol and Breast Cancer: MUC1 / E-cadherin/alpha-catenin / ErbB2 / Tumorigenesis / Metastasis / Transgenic Mice
|
profile
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Lutz, Charles
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NK Cell Receptor Recognition of Oral Cancers; KIR Gene Regulation in NK Cells
|
profile
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|
Mannino, David
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Correlates with COPD in assessing lung cancer risk (BOLD Project)
|
profile
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|
Mansour, Heidi
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Design of Multifunctional Nanoparticles for Pulmonary Inhalation Aerosol Delivery for Lung Cancer; Controlled Dual-Drug Delivery
|
profile
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Mao, Catherine
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Wnt signaling
|
profile
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|
Mardini, Houssam
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Chemoprevention of Colorectal Adenomas
|
profile
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Marti, Fransec
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iTreg suppressor T cell regulation by PPAR-gamma and retinoic acid receptor activity
|
profile
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Martin, Catherine
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Breaking the Cycle Smoking Intervention with Youth in Families Dealing with Lung Cancer; Modafinil aid for smoking cessation
|
profile
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Massarweh, Suleiman
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Tumor Regression in a Model of Estrogen Receptor-Positive, HER-2/neu-Positive Breast Cancer
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profile
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McDonagh, Kevin
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Immunotherapy, Chemotherapy and Targeted Molecular Therapy in Both Early and Advanced/Refractory NHL & CL
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profile
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McGarry, Ronald
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Stereotactic Body Radiation in Lung Cancer
|
profile
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McGillis, Joseph
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Regulation of B Cell Development; Genetic Regulation of Tumoricidal versus Tumor Promoting Macrophage Phenotypes
|
profile
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|
McGrath, Patrick
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Breast Cancer evaluation and treatment
|
profile
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McKenzie, Shaun
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Surgical oncology with interests in gastrointestinal oncology, hepatobiliary and pancreatic surgery, melanoma and sarcoma
|
profile
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McNamara, Patrick
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Drug transport pathways in cancer expression and treatment
|
profile
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Mellon, Isabel
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Nucleotide Excision Repair in skin and lung cancer
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profile
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Miller, Rachel Ware
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Gynecologic oncology
|
profile
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|
Morris, Andrew
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Lysophospholipid mediators in ovarian cancer
|
profile
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|
Moscow, Jeffrey
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Anti-Metabolites, Gene Methylation/De-Methylation and Thiamine Starvation Approaches Against Breast Cancer
|
profile
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Mullett, Timothy
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Lung cancer evaluation & treatment
|
profile
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Nelson, Peter
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MicroRNA Involvement in Brain Pathogenesis
|
profile
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Niaz, Qaiser
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Hematology and Oncology
|
profile
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|
Nickl, Nicholas
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Prevention of Sporadic Colorectal Adenomas with Celecoxib; colorectal & esophageal cancer screening effectiveness
|
profile
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Noonan, Daniel
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Retinoic Acid Targeting Lung Cancer; Tuberin, Tuberous Sclerosis 2 and ER-alpha gene Associated Targets in LAM Disease
|
profile
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|
O'Connor, Kathleen
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Integrin, PKA/cAMP, Rho/ROK and transcription in regulating cell motility, invasion and metastasis
|
profile
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Orren, David
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WRN and RecQ Helicase Function, Checkpoint Signaling & DNA Repair in Cancer & Aging
|
profile
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Paumi, Christian
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ABC transporter Ycf1p, multidrug resistance-associated protein, regulation in yeast
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profile
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Pavlik, Edward
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Ovarian Cancer Screening in Kentucky
|
profile
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Pearce, Kevin
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Improving Colorectal Screening
|
profile
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Pearson, Kevin
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Impact of perinatal voluntary exercise and diet on carcinogenesis, glucose sensitivity and motor coordination in offspring
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profile
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Peterson, Martha
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Modifying lung cancer apoptosis through alternative RNA splicing
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profile
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Plattner, Rina
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PDGF signaling & Abl kinase regulation in normal and malignant cells
|
profile
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Randall, Marcus
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Radiation in the Multimodality Treatment of Gynecologic Cancers
|
profile
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Rangnekar, Vivek
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Apoptotic and Survival Signaling Pathways in Prostate Cancer: PAR-4, PTEN and AKT Gene Reg.; leukemia/lymphoma growth regulation
|
profile
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Ren, Hongmei
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Mitochondrial oxidative metabolism and the role of lipid phosphatases in cholesterol and triglyceride synthesis
|
profile
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Rinehart, John
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Combination Chemotherapy, Immunotherapy, Dexamethasone and Molecular Therapy for Urologic & Lung Cancers and Melanoma
|
profile
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|
Rohr, Jurgen
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Synthesis of Novel Aureolic Acid- and Gilvocarcin-Type Anti-Cancer Agents Using Combinatorial Biosynthesis
|
profile
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Romond, Edward
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Combination & molecular-targeted therapies for advanced and metastatic breast cancer
|
profile
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Roszman, Thomas
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Extracellular Matrix, Calpain, Cancer and T-Cell Migration and Invasion
|
profile
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Rowland, Randall
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A Multi Center Randomized Phase III Study of Oncophage Versus Observation in Patients with High Risk of Recurrence
|
profile
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Rudy, David
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Tobacco Prevention/Cessation Education: Medical Students
|
profile
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Rychahou, Piotr
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PHLPP, Akt2, N-myc, PI3K, Integrin & VEGF regulation in proliferation, tumorigenesis & metastasis; colorectal cancer & neuroblastoma
|
profile
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|
Saito, Hiroshi
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PI3-Kinase and homeobox-1 in pancreatic duct cell regeneration/differentiation; aging, endotoxic stress and inflammatory response
|
profile
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Sarge, Kevin
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Heat Shock Factors, Protein Phosphatase A2 & Cell Cycle Bookmarking
|
profile
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|
Schoenberg, Nancy
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Appalachian Wellness & Cancer Prevention; Cervical Cancer; Colorectal Screening for Patients with Multiple Morbidities
|
profile
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Seamon, Leigh
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Combination therapy for gynecologic malignancies
|
profile
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She, Qing-Bai
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Integration of PI3K/AKT and RAS/RAF/MEK/ERK signaling in tumors; Translational control of cancer progression; Drug resistance and target identification
|
profile
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Shelton, Brent
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Biostatistical analysis of laboratory, clinical and epidemiologic studies
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profile
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Sheng, Tao
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Hedgehog & Wnt signaling in gastrointestinal cancers
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profile
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Shi, Xianglin
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Mechanisms of As-, NI(II), CR(VI) induced carcinogenesis; Apple Peel Extract protection against UV-induced Carcinogenesis
|
profile
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Snow, Ernest C.
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Growth Regulation and Therapy of Leukemias and Lymphomas: Cell cycle progression in normal and malignant B cells
|
profile
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Spear, Brett
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AFP/Afr1: Gene cloning, liver gene regulation; Oxidative stress, PCBs, NF-kB, Hepatocarcinogenesis; leukemia & lymphoma regulation
|
profile
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Spielmann, Peter
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Structure of damaged DNA & its role in carcinogenesis; Psoralen, PCB-DNA adducts; modulation of G-Protein signal transduction
|
profile
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St Clair, Daret
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Oxidative Stress; MnSOD Expression & Regulation; Tumor Suppression; Tissue Protection; Cardiac Toxicity
|
profile
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St Clair, William
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Radiation Resistance, Redox Modulation; NF-kB & MnSOD in Androgen-Independent Prostate Cancer; parthenolide radiosensitization
|
profile
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Strup, Stephen
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A Multi-Center, Randomized Phase 3 Study of Adjuvant Oncophage vs. Observation in Patients with High Risk of Recurrence After Surgical Treatment for Renal Cell Carcinoma
|
profile
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Studts, Jamie
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Decision-Making and tobacco-related malignancy
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profile
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Swanson, Hollie
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AHR-Protac, aryl hydrocarbon receptor antagonist; Downstream Gene Regulation; Dioxin Tumor Promotion; Keratinocytes
|
profile
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Szabunio, Margaret
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Women's radiology with an emphasis on early detection of breast cancer using new and emerging technologies, including elastography and tomosynthesis
|
profile
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Tai, Hsin-Hsiung
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15-OH Prostaglandin dehydrogenase; role in tumorigenesis & tumor suppression
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profile
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Testa, Stephen
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Repairing RNA Transcripts Linked to Lung and Breast Cancer
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profile
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Thompson, John S
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Pathogenesis of acute graft-vs-host disease
|
profile
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Thorson, Jon
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Developing antibiotics and anticancer drugs from natural products
|
profile
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Tucker, Thomas
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Cancer Prevention & Control; Patterns of Care; Diet & molecular correlates of colon carcinogenesis
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profile
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Ueland, Frederick
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Combination Surgery, Chemotherapy, Radiation and Immunotherapy for Gynecologic Cancers
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profile
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Valentino, Joseph
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Microvascular reconstruction following chemotherapy and radiation in head & neck cancer patients
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profile
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Van Lanen, Steven
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Albomycin and Peptidyl-Uridinyl Nucleoside Antibiotics from Streptomyces sp. as Anti-Cancer Anti-Metabolites
|
profile
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|
Van Meter, Emily
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Cancer biostatistics with an emphasis on adaptive dose finding clinical trial designs
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profile
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Van Nagell Jr, John
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Ovarian Cancer Screening in Kentucky
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profile
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Van Zant, Gary
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Effect of aging on stem cells and their predisposition to leukemia, lymphoma and myelodysplastic syndrome; the tumor suppressor function of latexin in cancer
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profile
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Vander Kooi, Craig
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Structural Studies of Flt3 Activation and Inhibition in AML; Inhibition of VEGF signaling through selective targeting of Neuropilin
|
profile
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Villano, John
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Neuro-oncology
|
profile
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Vore, Mary
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Modulation of hepatocyte ABC transporter expression; oatp1/2, mrp2, MDR1, ntcp; xenobiotics; MRP1 Transporter and Oxidative Stress
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profile
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Wackerbarth, Sarah
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Colorectal Screening Decisions: Patients and Physicians
|
profile
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Wang, Chi
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Cancer biostatistics with an emphasis on high-throughput data analysis, gene set enrichment analysis, gene signature identification, and FDR control
|
profile
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Wang, Qingding
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p27, CDK, PTEN, NF-kB, GSK-3, c-Jun NH2-terminal kinase, MAPK, and Neurotensin regulatory actions in human colon epithelial cells
|
profile
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Wang, Qingjun
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Autophagy
|
profile
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Wang, Zhigang
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Molecular Dissection of Nucleotide Excision Repair; Mechanisms of DNA Lesion Bypass in Eukaryotes
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profile
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Watt, David
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Development of photoactive analogs of natural products for elucidating receptor binding
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profile
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Wei, Qiou
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The role of reactive oxygen species in tumorigenesis and cancer progression
|
profile
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Weiss, Heidi
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Biostatistical design and analysis of laboratory, clinical and epidemiologic studies;
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profile
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Wittenberg-Lyles, Elaine
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Hospice caregivers, communication and health literacy
|
profile
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Wu, Yadi
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Snail regulation in cell migration and invasion; epithelial-mesenchymal interactions; tumor growth and metastasis
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profile
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Wyatt, Stephen
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Health Promotion and Disease Prevention
|
profile
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Xu, Ren
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Integrated microenvironmental signals in cancer development and progression
|
profile
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Yang, Xiuwei
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Tumor-microenvironment interaction; laminin, ErbB, Integrin, claudin, cadherin, tetraspanins CD151/CD9
|
profile
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Yang, Hsin-Sheng
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Mechanism(s) of Pdcd4 tumor suppressor in colon & lung cancer; oncogene signaling: JNK, c-Jun, AP-1, Beta-catenin
|
profile
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Yannelli, John
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Optimization of Dendritic Cell-Based Immunotherapy in NSCLC; Lymphocyte antigen characterization
|
profile
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Young, Alfred Byron
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Neurosurgery, Gamma Knife Radiosurgery and Management of Peritumoral Brain Edema in Patients with Malignant Brain Neoplasms
|
profile
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Zhou, Peter Binhua
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HER2 expression; Wnt, Hedgehog and Snail; PI-3K/Akt & HIF-1 expression and signaling in malignancy; Breast cancer
|
profile
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Zhu, Haining
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Biomarker Discovery and Mechanistic Studies in Prostate Cancer Using Targeted Proteomic Approaches
|
profile
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Zwischenberger, Jay
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Surgical and adjuvant approaches to lung cancer
|
profile
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