| Faculty Name | Project Name | Web |
| Adams, Val | EGFR Targeted Nanoparticles to Oversome Paclitaxel-Resistant Breast Cancer |
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| Ain, Kenneth | Novel Chemotherapy of Radioiodine-Unresponsive Thyroid Carcinomas; Sodium-Iodine Symporter Transcriptional Repression |
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| Aldrich, Timothy | Lung Cancer in Kentucky - Environmental/Occupational Factor |
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| Alexander, Linda | Organizational, Cultural and Individual Barriers Associated with Utilization of a Worksite Tobacco Cessation Program |
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| Anderson, Bradley | Anti-topoisomerase aerosols for lung cancer therapy; combinatorial development of blood-stable Camptothecins |
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| Andrykowski, Michael | Psychological and Behavioral Impact of Cancer Screening and Cancer-Related Fatigue |
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| Armstrong, Debra | Breast and Cervical Cancer Coalitions |
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| Arnold, Susanne | ChemoRx & Low Dose Radiation for SCLC, NSCLC, Head & Neck Cancer, Metastatic Disease; 5th District Lung Cancer Program |
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| Bae, Younsoo | Multifunctional Nanoassemblies for Cancer Targeted Combination Drug Delivery |
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| Baron, Andre | Ovarian and Lung Cancer Biomarkers; Proteomics and sEGFR |
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| Bayliff, Sherry | Management of Children with Attention Impairment following Cancer Treatment |
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| Black, Esther | Genomic DNA Array analysis of oncogenic signaling pathways; MicroRNA expression and responses to chemotherapy |
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| Bondada, Subbarao | Growth & differentiation of B-Lymphocytes; BCR & Co-Receptor signaling & polymorphisms; leukemias & lymphomas |
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| Brown, Stephen | Radioprotective Agents in NSCLC Therapy |
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| Bryson, J. Scott | Growth Reg. and Rx of Leukemias & Lymphomas: Graft-versus-tumor (GVT) and (GVHD); BMT Toxicities in Aging; Allogeneic Rx in Lung Cancer |
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| Bummer, Paul | Development of Dosage Forms and Delivery Systems for Anti Tumor Agents |
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| Chen, Min | Integrin, cell motility and invasion in breast carcinoma |
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| Chendil, Damodaran | Mechanism(s) of Action of Novel Herbal Agents Against Prostate & Breast Cancers |
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| Chi, Young-in | Menin: Tumor suppressor and gestational diabetes related protein |
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| Cibull, Michael | Ovarian Tissue Bank/GOG |
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| Clayton, Richard | Tobacco etiology research network analysis; Tobacco-related health disparities research network (TReND) |
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| Cohen, Donald | Modulation of Anti-Tumor Immunity via IL-10 Production by Non-Small Cell Lung Carcinomas |
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| Craven, Rolf | Pgrmc1/Hpr6 Expression and MDR in Breast Cancer; EGFR Targeting in Lung Cancer |
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| Crooks, Peter | Drug Design/Development; Natural Products;Radiosensitization; Heat Shock Response; Parthenolides, Nicotinic Antagonists |
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| Crosby, Richard | STDs (HPV) and tobacco synergy in cervix cancer incidence |
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| Curry, Thomas | Ovarian metalloproetinases and reproductive aging |
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| D'Orazio, John | Melanoma, Forskolin, MC1R, Melanin, UV-Damage and DNA repair |
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| Desimone, Philip | A Phase 2 Study of ARQ 501 in Combination wit Gemcitabine in Adult Patients with Treatment Naive, Unresectable Pancreatic Adenocarcinoma |
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| Dignan, Mark | Native Network Cancer Resources Center; ACCN; Go Sun Smart; Nutrition & Physical Activity; KYPRC; Rural Screening |
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| Durbin, Eric | KCR Data Matching Project |
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| Dwoskin, Linda | Nicotinic Receptor Antagonists: Development of novel treatments for nicotine addiction |
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| Elliott, Gregory | Development and evaluation of Purine-Based AdSS Inhibitors |
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| Eum, Sung Yong | PCB-Induced Endothelial Dysfunction and Cancer Metastasis |
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| Evers, B. Mark | Molecular mechanisms of gastrointestinal development, growth and malignancy; Functional gene expression & signaling pathways |
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| Fannon, Michael | Computer Modeling of Perlecan as a Vascular Regulator |
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| Ferraris, Victor | Effect of Aprotinin on Transfusion Requirements During Surgery for Lung or Esophogus Cancer |
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| Fleischman, Roger | Cytokine, Immunotherapy and Chemotherapy for Lymphoma |
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| Fleming, Steven | Breast and Prostate Cancer Patterns of Care Study |
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| Fried, Michael | Cooperative interactions and interchromosomal gene regulation in DNA repair |
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| Gairola, Chandrachuranan | Genetic Polymorphism and Lung Cancer: Animal Models of Tobacco Carcinogenesis |
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| Gao, Tianyan | Ca++ channels, Akt phosphatase and PHLPP in tumorigenesis |
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| Glauert, Howard | Antioxidants, Cigarette Smoke, Semi-Volatile PCBs, Hepatic Toxicity/Tumorigenesis, NF-kB, Apoptosis; Nutrition & Prevention of Cancer |
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| Greenwood, Martha | Children's Oncology Group |
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| Gu, Liya | DNA Mismatch Repair Deficiency and Leukemia Relapse |
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| Gu, Qihai | Pulmonary stresses in small cell lung cancer: Neurogenic mechanisms |
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| Hahn, Ellen | Tobacco Policy Research Program and Clean Indoor Air Partnership |
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| Hatcher, Jennifer | Promoting Mammography in African American Women Visiting the Emergency Department |
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| Hayslip, John | Phase II - III studies of Chronic Lymphocytic Lymphoma, Non-Hodgkins Lymphoma, |
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| Hennig, Bernhard | Superfund NIEHS: Dietary protection vs oxidative damage from PCBs contributing to chronic disease |
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| Hilt, James | NIRT: Novel Magnetically and Thermally Responsive Nanoparticles for Cancer Treatment |
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| Hirschowitz, Edward | Autologous Dendritic Cell Vaccines in NSCLC; autoantibody markers of NSCLC; novel lung tumor antigens |
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| Hopenhayn, Claudia | Monitoring the Impact of a Prophylactic HPV Vaccine on HPV types in Cervical Cancer using Tissues for Validation |
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| Howard, Dianna | Targeted ablation of stem cells in leukemias/lymphomas; in vivo model of leukemia stem cells |
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| Jennings, Chester | Leukemias and Lymphomas: Histopathology of B-cell lymphoma impacted by signal transduction regulation |
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| Jia, Jianhang | Hedgehog signaling; dMST as a tumor suppressor |
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| Jones, Jeffrey | Coordinated school health youth risk behavior survey project |
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| Kaetzel, Charlotte | Polymeric Immunoglobulin Receptor Dysregulation in Colon & Lung Cancer; Bacterial-Epithelial Interactions in Colon Inflammation |
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| Kaetzel, David | NM23-H1 Isoform Endonuclease, DNA Repair, Suppression of Mutator Phenotype and Metastasis; PDGF-A gene enhanceosome |
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| Kaplan, Alan | Hypoxia-driven macrophage-mediated immunotherapy of lung cancer; T-cell regulation; modulation of GVHD and GVL in BMT |
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| Kenady, Daniel | TNFerade Biologic with-5-FU and Radiation Therapy for Advanced Pancreatic Cancer; IRX-2 in SCC of the Head & Neck |
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| Key, Bryan | Combination Chemotherapy, Immunotherapy and Targeted Molecular Therapy for Gastrointestinal Cancers |
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| Kilgore, Michael | Transcriptional Control of Differentiation, Proliferation & Apoptosis Through PPAR-gamma: Breast Cancer |
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| Kim, Kyung-Bo | Identify/Develop and Validate Novel Drug Targets (AHR, Proteasomes, Angiogenesis) and Targeting Agents |
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| Kirsh, Kenneth | Overcoming Barriers to Depression Recognition in Cancer |
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| Koch, Alvaro | Prevalence and Impact of Hepatitis B and C in Rural Kentucky |
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| Kohler, Heinz | Development of 2nd/3rd Generation Antibodies Against HER-2/neu Receptor in Lung Cancer |
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| Kudrimoti, Mahesh | Risk and Outcomes of Mucositis in Subjects Being Treated for Breast, Colorectal, Head and Neck, Non-small Cell Lung or Ovarian Cancers |
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| Kyprianou, Natasha | Targeted Modulation of Signaling Pathways in Prostate Cancer, BPH, Anoikis and Apoptosis; TGF-B, Quinazolines |
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| Lee, Lu-Yuan | Cellular Mechanisms Underlying Pulmonary Stresses in Small Cell Lung Cancer |
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| Lee, Wooin | Functional and Molecular Studies of OATP1B3 in Colon Cancer |
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| Leggas, Marcos | Clinical Development of Anti-Cancer Agents; Pharmacokinetics, Nanoparticles, ABC Transporter, DB-67 |
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| Li, Guo-Min | DNA Mismatch Damage Response Elements in Cancer Prevention/Progression |
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| Li, Tonglei | Development of Novel Ligand-Drug Hybrid Nanocrystals to Target Breast Cancer |
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| Li, Jing | PKC, PKD, neurotensin, Rap 1, EPAC, Ox Stress, Rho/ROK/PKC-delta and hedgehog regulation in intestinal cell survival & proliferation |
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| Liu, Chunming | B-Catenin, APC, Wnt signaling and colon tumorigenesis |
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| Luo, Guangxiang | Mechanism of Hepatitis C Virus Infection and Replication |
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| Luo, Jia | Alcohol and Breast Cancer: MUC1 / E-cadherin/alpha-catenin / ErbB2 / Tumorigenesis / Metastasis / Transgenic Mice |
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| Lutz, Charles | NK Cell Receptor Recognition of Oral Cancers; KIR Gene Regulation in NK Cells |
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| Mannino, David | Correlates with COPD in assessing lung cancer risk (BOLD Project) |
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| Mansoor, Heidi | Design of Multifunctional Nanoparticles for Pulmonary Inhalation Aerosol Delivery for Lung Cancer; Controlled Dual-Drug Delivery |
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| Mardini, Houssam | Chemoprevention of Colorectal Adenomas |
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| Marti, Fransec | iTreg suppressor T cell regulation by PPAR-gamma and retinoic acid receptor activity |
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| Martin, Catherine | Breaking the Cycle Smoking Intervention with Youth in Families Dealing with Lung Cancer; Modafinil aid for smoking cessation |
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| Massarweh, Suleiman | Tumor Regression in a Model of Estrogen Receptor-Positive, HER-2/neu-Positive Breast Cancer |
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| McDonagh, Kevin | Immunotherapy, Chemotherapy and Targeted Molecular Therapy in Both Early and Advanced/Refractory NHL & CLL |
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| McGarry, Ronald | Stereotactic Body Radiation in Lung Cancer |
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| McGillis, Joseph | Regulation of B Cell Development; Genetic Regulation of Tumoricidal versus Tumor Promoting Macrophage Phenotypes |
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| McNamara, Patrick | Drug transport pathways in cancer expression and treatment |
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| Mellon, Isabel | Nucleotide Excision Repair in skin and lung cancer |
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| Mendenhall, Michael | Cell Division Checkpoints: Genetic and Biochemical Studies of a Yeast CDK inhibitor Interaction |
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| Mohan, Royce | Novel Modular Vascular Patterning Assay for HTS |
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| Morris, Andrew | Lysophospholipid mediators in ovarian cancer |
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| Moscow, Jeffrey | Anti-Metabolites, Gene Methylation/De-Methylation and Thiamine Starvation Approaches Against Breast Cancer |
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| Muse, Kenneth | Evaluation of the safety of Asoprisnil in Subjects with Uterine Leiomyomata |
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| Nickl, Nicholas | Prevention of Sporadic Colorectal Adenomas with Celecoxib; colorectal & esophageal cancer screening effectiveness |
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| Noonan, Daniel | Retinoic Acid Targeting Lung Cancer; Tuberin, Tuberous Sclerosis 2 and ER-alpha gene Associated Targets in LAM Disease |
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| O'Connor, Kathleen | Integrin, PKA/cAMP, Rho/ROK and transcription in regulating cell motility, invasion and metastasis |
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| Orren, David | WRN and RecQ Helicase Function, Checkpoint Signaling & DNA Repair in Cancer & Aging |
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| Pan, Bintao | Mechanism of Ras Protein Action in Cell Division & Tumor Progression |
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| Paumi, Christian | ABC transporter Ycf1p, multidrug resistance-associated protein, regulation in yeast |
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| Pearce, Kevin | Improving Colorectal Screening |
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| Pearson, Kevin | Impact of perinatal voluntary exercise and diet on carcinogenesis, glucose sensitivity and motor coordination in offspring |
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| Peterson, Martha | Modifying lung cancer apoptosis through alternative RNA splicing |
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| Pierce, Andrew | Genomic Instability, Double-Stranded DNA Repair, Alternate forms of Homologous Recombination; Bloom Syndrome |
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| Plattner, Rina | PDGF signaling & Abl kinase regulation in normal and malignant cells |
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| Randall, Marcus | Radiation in the Multimodality Treatment of Gynecologic Cancers |
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| Rangnekar, Vivek | Apoptotic and Survival Signaling Pathways in Prostate Cancer: PAR-4, PTEN and AKT Gene Reg.; leukemia/lymphoma growth regulation |
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| Rinehart, John | Combination Chemotherapy, Immunotherapy, Dexamethasone and Molecular Therapy for Urologic & Lung Cancers and Melanoma |
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| Rohr, Jurgen | Synthesis of Novel Aureolic Acid- and Gilvocarcin-Type Anti-Cancer Agents Using Combinatorial Biosynthesis |
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| Romond, Edward | Combination & molecular-targeted therapies for advanced and metastatic breast cancer |
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| Roszman, Thomas | Extracellular Matrix, Calpain, Cancer and T-Cell Migration and Invasion |
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| Rowland, Randall | A Multi Center Randomized Phase III Study of Oncophage Versus Observation in Patients with High Risk of Recurrence |
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| Rudy, David | Tobacco Prevention/Cessation Education: Medical Students |
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| Rychahou, Piotr | PHLPP, Akt2, N-myc, PI3K, Integrin & VEGF regulation in proliferation, tumorigenesis & metastasis; colorectal cancer & neuroblastoma |
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| Saito, Hiroshi | PI3-Kinase and homeobox-1 in pancreatic duct cell regeneration/differentiation; aging, endotoxic stress and inflammatory response |
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| Sarge, Kevin | Heat Shock Factors, Protein Phosphatase A2 & Cell Cycle Bookmarking |
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| Schoenberg, Nancy | Appalachian Wellness & Cancer Prevention; Cervical Cancer; Colorectal Screening for Patients with Multiple Morbidities |
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| Schrieber, Judith | Optimism, Locus of Control, Spirituality and Meaning in Life in Cancer Patients |
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| Schwarze, Steven | Induction of cell senescence for therapy of prostate cancer; Death receptor; Ubiquitin-proteasome system; TRAIL targeting |
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| Shelton, Brent | Biostatistical analysis of laboratory, clinical and epidemiologic studies |
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| Sheng, Tao | Hedgehog & Wnt signaling in gastrointestinal cancers |
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| Shi, Xianglin | Mechanisms of As-, NI(II), CR(VI) induced carcinogenesis; Apple Peel Extract protection against UV-induced Carcinogenesis |
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| Snow, Ernest C. | Growth Regulation and Therapy of Leukemias and Lymphomas: Cell cycle progression in normal and malignant B cells |
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| Spear, Brett | AFP/Afr1: Gene cloning, liver gene regulation; Oxidative stress, PCBs, NF-kB, Hepatocarcinogenesis; leukemia & lymphoma regulation |
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| Spielmann, Peter | Structure of damaged DNA & its role in carcinogenesis; Psoralen, PCB-DNA adducts; modulation of G-Protein signal transduction |
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| St Clair, Daret | Oxidative Stress; MnSOD Expression & Regulation; Tumor Suppression; Tissue Protection; Cardiac Toxicity |
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| St Clair, William | Radiation Resistance, Redox Modulation; NF-kB & MnSOD in Androgen-Independent Prostate Cancer; parthenolide radiosensitization |
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| Stinchcomb, Audra | Transdermal Delivery of Cannabinoids for Treatment of Cancer Patients |
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| Stoops, William | Behavioral aspects of nicotine addiction and smoking cessation; Internet-Based Voucher Incentive System |
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| Strup, Stephen | A Multi-Center, Randomized Phase 3 Study of Adjuvant Oncophage vs. Observation in Patients with High Risk of Recurrence After Surgical Treatment for Renal Cell Carcinoma |
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| Swanson, Hollie | AHR-Protac, aryl hydrocarbon receptor antagonist; Downstream Gene Regulation; Dioxin Tumor Promotion; Keratinocytes |
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| Tai, Hsin-Hsiung | 15-OH Prostaglandin dehydrogenase; role in tumorigenesis & tumor suppression |
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| Tanner, Bonnie | Health Education through Extension Leadership (HEEL) |
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| Testa, Stephen | Repairing RNA Transcripts Linked to Lung and Breast Cancer |
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| Toborek, Michal | Pathways of endothelial cell damage and Blood-Brain Barrier breakdown in brain metastasis. |
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| Tucker, Thomas | Cancer Prevention & Control; Patterns of Care; Diet & molecular correlates of colon carcinogenesis |
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| Ueland, Frederick | Combination Surgery, Chemotherapy, Radiation and Immunotherapy for Gynecologic Cancers |
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| Valentino, Joseph | Microvascular reconstruction following chemotherapy and radiation in head & neck cancer patients |
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| Van Lanen, Steven | Albomycin and Peptidyl-Uridinyl Nucleoside Antibiotics from Streptomyces sp. as Anti-Cancer Anti-Metabolites |
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| Van Nagell Jr., John | Ovarian Cancer Screening in Kentucky |
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| Van Zant, Gary | Latexin as a key regulatory target of stem cell modulation in tumorigenesis and cancer treatment; leukemia stem cell regulation & targeting |
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| Vander Kooi, Craig | Structural Studies of Flt3 Activation and Inhibition in AML; Inhibition of VEGF signaling through selective targeting of Neuropilin |
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| Vore, Mary | Modulation of hepatocyte ABC transporter expression; oatp1/2, mrp2, MDR1, ntcp; xenobiotics; MRP1 Transporter and Oxidative Stress |
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| Wackerbarth, Sarah | Colorectal Screening Decisions: Patients and Physicians |
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| Wang, Zhigang | Molecular Dissection of Nucleotide Excision Repair; Mechanisms of DNA Lesion Bypass in Eukaryotes |
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| Wang, Qingding | p27, CDK, PTEN, NF-kB, GSK-3, c-Jun NH2-terminal kinase, MAPK, and Neurotensin regulatory actions in human colon epithelial cells |
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| Waterstrat, Amanda | Genetic regulation of hematopoietic stem cell number |
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| Watkins, John | The development of cancer beliefs in older rural Appalachian women |
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| Weiss, Heidi | Biostatistical design and analysis of laboratory, clinical and epidemiologic studies; |
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| Wu, Yadi | Snail regulation in cell migration and invasion; epithelial-mesenchymal interactions; tumor growth and metastasis |
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| Wyatt, Stephen | Health Promotion and Disease Prevention |
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| Yang, Hsin-Sheng | Mechanism(s) of Pdcd4 tumor suppressor in colon & lung cancer; oncogene signaling: JNK, c-Jun, AP-1, Beta-catenin |
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| Yannelli, John | Optimization of Dendritic Cell-Based Immunotherapy in NSCLC; Lymphocyte antigen characterization |
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| Young, Alfred Byron | Neurosurgery, Gamma Knife Radiosurgery and Management of Peritumoral Brain Edema in Patients with Maligant Brain Neoplasms |
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| Zhou, Peter Binhua | HER2 expression; Wnt, Hedgehog and Snail; PI-3K/Akt & HIF-1 expression and signaling in malignancy; Breast cancer |
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| Zhu, Haining | Biomarker Discovery and Mechanistic Studies in Prostate Cancer Using Targeted Proteomic Approaches |
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Academics |
Service | Research |
UK HealthCare | UK A-Z 
